Family Home and Life: Kids Painting Projects Recycled

I surely do have a bored out of school kindergartener. I?m always trying to find ways to keep her busy. Now that she is an educated school girl it seems that Gramma isn?t as much fun as she use to be pre school days. That?s so sad!!! For me anyway?..well. ?I?m working on that problem but I am having a hard time engaging her; ?she wants to play with her friends.

It's not a clear picture but you can see the boredom on her face. I pulled out all the left behind paintings that the little kids left behind and some other discarded paper and told her I needed them cut into strips and the other pile needed to be circle punched for an art project I wanted to do.

She got to work and had a big mess in progress and after I put Itty Bitty down to nap I sat down with her to do my project. Of course she decided to?help me. This is a good way to use up and recycle those papers that would just be thrown away.

We used the punched circles to make new art. ?I talked to her about using them to make patterns using the circles with the same colors.

One used only circles that looked like they came from the same ?family? or the from the same paintings.

One circle picture was totally random.

I 'needed' a paper chain too so we glued some strips together from the cut paintings.

Our glue bottle was low and that is annoying waiting for it to run to the opening so we kept it upside down in an old mug between uses. Here's a weaving project we made with some paper strips. I tapped one end of each strip down to the backing paper and then we weaved the strips through. Then I secured all strip ends with a drop of glue.
She also decided to make something for the Fourth of July; a finger print painting. Well, I managed to keep her busy for an hour or so but then she was back to being bored. I?ll have to think up something new.

Copyright? Family Home and Life 2012 All Rights Reserved

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Gadget Lab Show: Galaxy S III, Microsoft Surface and Windows Phone 8

On this week's Gadget Lab Show, we give you a hands-on look at the Samsung Galaxy S III, discuss the Microsoft Surface and Windows Phone 8, and take a look at a few car-cigarette-lighter-powered gadgets.

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Michael Jackson's 15 Most Memorable Moments

With the three-year anniversary of the singer's death on June 25, take a look back at the highs and lows of his life and career.

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July 5 weighs in as potential Droid Incredible 4G LTE release date

Here we go again, right? A leaked shot shows a date, we all get our hopes up and then they are crushed when it changes.  Well, according to an internal Verizon document the Droid Incredible 4G LTE is gearing up to be in our hands on July 5. The device was officially announced back in May, and perhaps you'll recall our hands-on with it at CTIA, and Verizon initially stated that it would be available "in the coming weeks," and, well, more than a few weeks have passed since then. Keeping it mind that the all new Verizon plans kick in starting on June 28, having the device launch shortly after is a good way to get those customers back in to renew their contracts. The pricing currently shows at the $199 price point, a bit higher than we had hoped, but hopefully Verizon will add a rebate or something to bring that price down to the $99 - $150 range. Now we sit and wait, hoping that July 5 is the day.

Source: Droid-Life

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Goalless England and Italy go to penalties

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The fundamental Considerations for Picking out a Professional Tax ...

June 24th, 2012 by admin | Print

Another tax months are upon us and taxpayers are deciding the very best avenue for preparation of these returns. The general public choose professional tax preparer services to tackle the responsibility of properly completing and filing their returns.

Needless to say, many taxpayers already have relationships with tax practitioners. But deciding on a new taxes preparer is normal because making a switch is easy. Plus, unlicensed small tax practices have to stop operating by recent legal requirements. Tax preparers face mandates for CPE courses and renewal fees for Preparer Tax Identification Numbers.

Professionals with experience in tax preparation careers should understand how to create lasting relationships. Their objective is creating client loyalty. Additionally, experienced tax pros desire to grow by gathering new business.

Anyone being a tax preparer the very first time must establish a graphic that draws business. Both experienced and new tax practitioners will see so many people are trying to find the proper professional. The optimal selection for anyone may be the tax preparer that best understands the taxpayer?s individual circumstances. Some tax preparers usually do not prepare certain types of forms, including home office deductions. Others avoid taxpayers who claim the Earned Income Tax Credit.

Superb advice a tax preparer can render to prospective clients is pointing out the value of examining their prior year returns. Many people think they?ve simple tax statements but they really have plenty of complicated considerations. By seeing should they understand every line on their tax forms, they could measure the advantages of a specialist with tax preparer certification. Expertise in distinctive tax areas is specially important.

Tax professionals often must stress value of preparer knowledge. Way too many taxpayers are worried with price rather than accuracy. About 200 dollars isn?t unreasonable for an accurate tax return. But an inferior fee is justified in the event the return isn?t complete or accurate. People providing tax services without accuracy guarantees are cheap for any reason. Individuals that desire to assure all earnings are correctly reported and all available tax credits are calculated will select a true tax professional with a proper license and training.

Some taxpayers require greater than preparation of the returns. They also need a little accounting help for a apartment or income from independent contractor work. Most CPAs and several Enrolled Agents provide such bookkeeping services. Holding such designations will help tax preparers demonstrate which they possess extensive abilities.

In addition to accuracy guarantees, pricing, and professional credentials, tax practitioners distinguish themselves in alternative methods. Examples are providing extended work hours and year-round operation.

This entry was posted on Sunday, June 24th, 2012 at 12:01 pm and is filed under Taxes. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Tagged as: Considerations, preparation, Professional Tax Preparer, return, tax, tax practitioners, tax preparation, tax preparer, tax preparers, work

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AP Exclusive: Al-Qaida trains Norwegian to attack

STOCKHOLM (AP) ? A Norwegian man has received terrorist training from al-Qaida's offshoot in Yemen and is awaiting orders to carry out an attack on the West, officials from three European security agencies told The Associated Press on Monday.

Western intelligence officials have long feared such a scenario ? a convert to Islam who is trained in terrorist methods and can blend in easily in Europe and the United States, traveling without visa restrictions.

Officials from three European security agencies confirmed Monday the man is "operational," meaning he has completed his training and is about to receive a target. All spoke on condition of anonymity because they were not authorized to discuss the case publicly. They declined to name the man, who has not been accused of a crime.

"We believe he is operational and he is probably about to get his target," one security official said. "And that target is probably in the West."

A security official in a second European country confirmed the information, adding: "From what I understand, a specific target has not been established."

European security services, including in Norway, have warned in recent years of homegrown, radicalized Muslims traveling to terror training camps in conflict zones. Many of the known cases involve young men with family roots in Muslim countries.

But the latest case involves a man in his 30s with no immigrant background, the officials said. After converting to Islam in 2008, he quickly became radicalized and traveled to Yemen to receive terror training, one of the officials said. The man spent "some months" in Yemen and is still believed to be there, he said.

The official said the man has no criminal record, which would also make him an ideal recruit for al-Qaida.

"Not even a parking ticket," he said. "He's completely clean and he can travel anywhere."

The official would not specify what preventive measures were being taken but said "there is a well-established relationship between Western security services, and they share the information needed to prevent terrorism."

The officials declined to specify what makes them think the man is operational.

Signs that a would-be jihadist is ready for an attack could include the creation of so-called martyrdom videos for release online in conjunction with an attack, or an abrupt cutoff of communication and contacts with peers to avoid detection.

The man has not been accused of a crime in Norway, where traveling abroad to attend terror training camps is not a crime per se. In many European countries, suspects are not named unless they have been formally charged with a crime.

Yemeni military officials said they had information on Europeans training with al-Qaida in the southern part of the country but that they weren't aware of a Norwegian being among them. They spoke on condition of anonymity because they were not authorized to speak to the media.

CIA and FBI officials in the U.S. declined to comment on the AP report.

Trond Hugubakken, a spokesman for Norway's PST security service, also declined to comment on the case. He referred to a PST security assessment in February, which highlighted that "several" Islamic extremists have traveled from Norway to conflict zones to attend training camps.

Hugubakken acknowledged that converts who turn to violent extremism pose a particular challenge.

"Converts will have a different level of cover, especially if they have no criminal record," he said, adding that most Muslim converts do not turn to extremism.

There are several examples in Europe and the U.S. of converts linked to terror plots, from failed shoe-bomber Richard Reid, a British convert, to a Pennsylvania woman dubbed "Jihad Jane," who pleaded guilty last year to charges that she plotted to kill a Swedish cartoonist who caricatured Islam's Prophet Muhammad.

Norway saw the first convictions under its anti-terror laws this year when two men were given prison terms in January for plotting to attack a Danish newspaper that also had caricatured the Prophet Muhammad.

In March, Mullah Krekar, a radical Iraqi-born cleric who came to Norway as a refugee, was sentenced to five years in prison for making death threats against Norwegian officials and three Kurdish men he claimed had insulted Islam.

But Norway's most serious attacks happened last year at the hands of a right-wing, anti-Muslim extremist, Anders Behring Breivik, who admitted to killing 77 people in a bombing-and-shooting massacre on July 22. The self-styled militant's trial ended last week with conflicting claims about whether he is criminally insane. A verdict has been set for Aug. 24.

____

Associated Press writer Paisley Dodds in London, Intelligence Writer Kimberly Dozier and AP writer Eileen Sullivan in Washington and Ahmed al-Haj in Sanaa, Yemen, contributed to this report.

Associated Press

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Sr. Software Engineer (C/C++) at Sony Network Entertainment (San Francisco, CA)

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Negotiators closing in on student loan deal

WASHINGTON (AP) ? Congressional bargainers appeared to be closing in on a compromise that would head off a July 1 doubling of interest rates on federal loans to 7.4 million college students and end an election-year battle between President Barack Obama and Congress.

Senate aides from both parties said Friday the two sides were moving toward a deal on how to pay the measure's $6 billion price tag, the chief source of partisan conflict.

The goal is to push legislation through Congress next week so the current 3.4 percent interest rate on subsidized Stafford loans can be preserved for another year. A 2007 law gradually reduced interest rates on the loans but required them to balloon back to 6.8 percent this July 1 in a cost-saving maneuver.

On another front, the two sides were also close to an agreement to overhaul federal transportation programs, according to House and Senate aides from both parties. Negotiations were expected to continue through the weekend, with votes expected next week on either a major transportation bill or an extension of current programs, said the aides, who spoke on condition of anonymity to discuss details of the talks.

Obama said Saturday in his weekly radio and Internet address there was "no excuse for inaction."

"Right now, we are seven days away from thousands of American workers having to walk off the job because Congress hasn't passed a transportation bill. We are eight days away from nearly seven and a half million students seeing their loan rates double because Congress hasn't acted to stop it," Obama said. "This makes no sense."

For weeks, Obama has ridiculed Republicans for not moving quickly to prevent student loan interest rates from doubling, a stance that Democrats have hoped will boost his support among young voters who broadly backed him in the 2008 election. With college costs and student debt growing steadily, the issue ties directly into concerns about the economy and jobs that polls show dominate voters' worries.

Though some rank-and-file GOP lawmakers have opposed letting the government set the rates, Republican presidential challenger Mitt Romney and GOP congressional leaders have backed the one-year extension. The remaining dispute has been over how to pay for it.

Republicans have accused Obama of creating a phony issue and drawing out the battle in an attempt to reap political points. In late May, they proposed several options to pay for the measure, all of which were culled from budget savings Obama himself had proposed in the past, but they said the White House was ignoring them.

"Even though the White House refuses to respond to our bipartisan approach, Senate Democrats are finally working with us, and a solution is within reach ? despite the president's failure to act," said Don Stewart, spokesman for Senate Minority Leader Mitch McConnell, R-Ky.

The talks have involved aides to McConnell and Senate Majority Leader Harry Reid, D-Nev. Democrats said the White House has been kept abreast of the talks, while Republicans said House Speaker John Boehner, R-Ohio, has been kept informed but hasn't participated in the negotiations.

According to Democratic aides, negotiators are approaching a deal to cover the bill's costs by charging companies more to insure pensions and changing rules so companies take fewer tax deductions for their pension contributions. Reid proposed both of those ideas this month.

They said additional money would come from a list of options McConnell has offered, probably one to limit federal subsidies of undergraduates' loans to six years. The government does not begin charging interest on Stafford loans until after students graduate, which can take longer than six years.

"While we're not there, we're well down the road. I think we can get something done," Reid told reporters Thursday. He said McConnell and Boehner "are compromising just as we are and hope we can get something done."

If allowed to double, the higher 6.8 percent rate would apply only to new subsidized Stafford loans for undergraduates approved starting on July 1 and would not affect existing loans.

According to the Education Department, 7.4 million students are expected to get new Stafford loans in the year beginning July 1, with each borrowing an average $4,226. A doubling of interest rates would add about $1,000 to the costs of the average loan, which students typically pay off over 10 or more years.

The Federal Reserve Bank of New York said last month that student loan debt grew this year to $904 billion, even as other types of consumer debt were falling.

___

Associated Press writer Joan Lowy contributed to this report.

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Fitch Affirms Ford Credit Auto Lease Trust 2011-A

CHICAGO--(BUSINESS WIRE)--Fitch Ratings has affirmed four classes of notes issued by Ford Credit Auto Lease Trust 2011-A as detailed below:

--Class A-2 notes affirmed at 'AAAsf'; Outlook Stable;

--Class A-3 notes affirmed at 'AAAsf'; Outlook Stable;

--Class A-4 notes affirmed at 'AAAsf'; Outlook Stable;

--Class B notes affirmed at 'AAsf'; Outlook Stable.

The affirmations reflect the increase in credit enhancement since closing and strong collateral performance. Credit and residual performance has been well within Fitch's expectations to date. The Stable Outlook reflects Fitch's expectation that the notes will remain sufficiently enhanced to cover stressed loss levels consistent with the current ratings.

Fitch will continue to monitor economic conditions and their impact and the trust level performance variables and update the ratings accordingly.

Additional information is available at 'www.fitchratings.com'. The ratings above were solicited by, or on behalf of, the issuer, and therefore, Fitch has been compensated for the provision of the ratings.

The information used to assess these ratings was sourced from the issuer, periodic trustee reports, note valuation reports, and the public domain.

Applicable Criteria and Related Research:

--'Criteria for Rating U.S. Auto Lease ABS' May 14, 2012;

--'Global Structured Finance Rating Criteria' June 6, 2012.

Applicable Criteria and Related Research:

Global Structured Finance Rating Criteria

http://www.fitchratings.com/creditdesk/reports/report_frame.cfm?rpt_id=679923

Criteria for Rating U.S. Auto Lease ABS

http://www.fitchratings.com/creditdesk/reports/report_frame.cfm?rpt_id=678137

ALL FITCH CREDIT RATINGS ARE SUBJECT TO CERTAIN LIMITATIONS AND DISCLAIMERS. PLEASE READ THESE LIMITATIONS AND DISCLAIMERS BY FOLLOWING THIS LINK: HTTP://FITCHRATINGS.COM/UNDERSTANDINGCREDITRATINGS. IN ADDITION, RATING DEFINITIONS AND THE TERMS OF USE OF SUCH RATINGS ARE AVAILABLE ON THE AGENCY'S PUBLIC WEBSITE 'WWW.FITCHRATINGS.COM'. PUBLISHED RATINGS, CRITERIA AND METHODOLOGIES ARE AVAILABLE FROM THIS SITE AT ALL TIMES. FITCH'S CODE OF CONDUCT, CONFIDENTIALITY, CONFLICTS OF INTEREST, AFFILIATE FIREWALL, COMPLIANCE AND OTHER RELEVANT POLICIES AND PROCEDURES ARE ALSO AVAILABLE FROM THE 'CODE OF CONDUCT' SECTION OF THIS SITE.

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President Obama: We don't need an outsourcing pioneer in the Oval Office (Washington Bureau)

Share With Friends: | | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

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NY Legislature passes teacher eval disclosure bill

ALBANY, N.Y. (AP) ? Teacher evaluations will be kept secret from most taxpayers after state lawmaker's overwhelmingly passed Gov. Andrew Cuomo's bill Thursday, giving a major victory to teachers unions, who opposed wider disclosure of the appraisals.

Under Cuomo's bill, a teacher's evaluation will only be released to the parents and guardians of students in his or her class. Even armed with a poor rating, parents and guardians would find it difficult to remove their child from the class, supporters and opponents of the bill agreed. In addition, parents and guardians would not have access to evaluations of teachers outside their child's classroom, which would otherwise enable them to "shop" for a better teacher the following year.

Without the bill, all evaluations for teachers and principals would be public, based on a court decision.

"The intention of this bill is to avoid media exploitation," said Assemblywoman Ellen Jaffee, a Rockland County Democrat who sponsored the bill. She explained the state committed to evaluations and some disclosure when it applied for and accepted more than $700 million in federal funds last year under the Obama administration's Race to the Top competition to improve instruction.

She said that under a recent court decision forced by a New York Post lawsuit, teacher evaluations would start to be available beginning Aug. 15 to anyone under the Freedom of Information Act unless Cuomo's bill was enacted.

Teachers and their politically powerful unions were outraged at the release of New York City teacher evaluations in articles that compared the effectiveness of schools. Mayor Michael Bloomberg had argued full disclosure was the fastest and most effective way to improve instruction and motivate teachers.

Assemblyman Michael Simanowitz, a Queens Democrat, said he saw no reason to release the evaluations "except to sell newspapers."

"What sells newspapers better than a little controversy?" he asked in the two-hour floor debate. "How will the student be served by the newspapers having this information?"

The Senate passed the measure 58-1 while the Assembly passed it 118-17. But many of those in support said they were cornered into voting for a bill from Cuomo because the alternative ? full disclosure ? would be worse for teachers.

"It just seems like we have the torches and the pitchforks out and we're going after teachers," said Assemblyman Steve McLaughlin, a Greene County Republican and husband of a teacher. "I think in hindsight we should have told the feds to keep the $700 million ... we're branding these teachers."

Supporters defended the bill as part of improving education, which Cuomo said costs New York more than most states while getting only middle-range results.

"I believe the shakeup of education in New York state is a good thing and long overdue," said Assemblyman Michael Fitzpatrick, a Suffolk County Republican. "As a property tax payer on Long Island, I am tired of the shakedown I experience each and every year from the education system."

Other also argued for the accountability of disclosure.

"Data is now a fact of our lives," said Assembly Education Committee Chairwoman Catherine Nolan, a Queens Democrat. "And, yes, let's not sell our parents short: They have a right to know."

"I believe in disclosure, I want accountability," said Assemblyman Vito Lopez, a Brooklyn Democrat. "My first, second and third priority are the children of New York City."

Bloomberg said he understood this was a tough issue, but a critical one.

"I believe that parents have a right to full disclosure when it comes to information about their child's education, and I am disappointed that this bill falls short of that goal," Blooomberg said. "Parents need information to make good decisions about their children's schools."

The state's biggest union called it a win for teacher privacy.

"The governor and Legislature did the right thing by stopping the media from distorting and disseminating evaluation results," said Richard Iannuzzi, president of the New York State United Teachers union. "This bill accomplishes that goal and preserves the purpose of evaluations, which is to provide opportunity for continued growth and improvement."

"I believe it strikes the right balance between protecting teacher privacy and a parent's right to know," Cuomo said.

The Senate didn't agree to bring the measure to a vote until Thursday morning, the final day of the 2012 session.

"It's a compromise between a parent's right to know and some form of confidentiality," said Senate Majority Leader Dean Skelos, a Long Island Republican. "I'm sure it's going to be reviewed in the future," Skelos said.

"I have no intention of revisiting the bill in six months or a year," Cuomo said hours later, with Skelos at his side at a news conference.

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'Seeking A Friend For The End Of The World': The Reviews Are In!

Cataclysmic comedy starring Keira Knightley and Steve Carell has critics divided.
By Kevin P. Sullivan

Patton Oswalt and Steve Carell in "Seeking a Friend for the End of the World"
Photo:

Critics are decidedly split on Lorene Scafaria's "Seeking a Friend for the End of the World" and whether its cataclysmic hijinks are cute or phony.

Here is our roundup of reviews for "Seeking a Friend for the End of the World."

The Story
"At least it's an ambitious misfire from the filmmaker, screenwriter Lorene Scafaria making a rocky directing debut. The movie ponders what people would do with their final days if the end were a fait accompli. Will anarchy reign or will humanity win out? Will Dodge (Carell) and Penny (Knightley), relative strangers living in the same apartment building, find each other, and love, before the planet and the asteroid collide? Or will they die alone? Lots of potential for a really tragic love story — from here to eternity, literally." — Betsy Sharkey, Los Angeles Times

Steve Carell
"The sad sack in question is Dodge, a New York insurance salesman played by Steve Carell with the air of melancholy that serves, in his big-screen roles, as the functional equivalent of a 'Don't Call Me Michael Scott' T-shirt. Mr. Carell has a penchant for wounded and wistful romantic roles. Here, as in 'Dan in Real Life' and 'Crazy, Stupid, Love,' he is a nebbishy guy so far out of the Darwinian sexual rat race that he becomes irresistible to women." — A.O. Scott, The New York Times

Keira Knightley
"Penny feels equally underwritten, which leaves the awkward sight of Knightley, evidently still stuck in 'A Dangerous Method' mode, straining to appear girl-next-door cute while her facial expressions scream 'mental patient.' "— Peter Debruge, Variety

The Director
"Screenwriter Lorene Scafaria (the similarly fey 'Nick and Norah's Infinite Playlist') is over her head in her feature directing debut, unable to establish a consistent tone in a movie that flirts with black comedy, satire, romantic comedy and touchy-feely earnestness without really delivering any of them." — Lou Lumenick, New York Post

The Final Word
"What it doesn't have is a way of making sense of its comic and dramatic strains, together, in the same movie. Carell and Knightley work hard to bring life and truth to each stage of a dawning friendship. By the end, though, Dodge and Penny have had one too many affirming encounters that feel engineered, not lived." — Michael Phillips, Chicago Tribune

Check out everything we've got on "Seeking a Friend for the End of the World." For breaking news, celebrity columns, humor and more — updated around the clock — visit MTVMoviesBlog.com.

Related Videos

• MTV Rough Cut: 'Seeking A Friend For The End Of The World'

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T7C: Comment and Analysis Thread

You should click this, seriously!

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?A Tale of Seven Children?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
Well, since somebody brought this idea up and everyone keeps wanting to make one, except me.

Just kidding, but anyways, for ease of reading, post all of your Reviews here when you do them, also, I probably won't use this Thread too much, and with Character Analysis', maybe use just one Post, but edit it as time goes on?

- zody

P.S: Go free, my Children! Flock to the skies and comment each other to death!

"You think you know hate, misery, sorrow, loneliness and anger? Take all of these emotions you'd feel in your lifetime and times them by 100, then you know me." - Me

"People will hurt you in life, but when they do, just shrug it off, tell em to get f**ked and keep your head high, soldier" - My Grandad

"You know me? Do you really? I'm like a poisoned lolly, nice out the outside, but on the inside I could kill you easily." - Me

zody

Member for 2 years

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About the characters, why do that? Character's personalities, story, and all in general things about a character change over time, whether it be small or major development. I personally think it's a great way to analyze and compare how a character use to be at the beginning of his story to how he or she is at the end of a story. But I -guess- if you guys want to edit them, then alright. Although one more thing, it's pretty hard to edit something when more newer posts are being made and it will be less and less more looked at it as time goes on.

The Great Thundorz

Member for 0 years

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@Thundorz: I thought of that after posting, but I'm too lazy to change it. Anyways, I'm off to bed soon, so I'm not gonna be able to post for a few days since I'm going down the coast for 8 days. I'll try and keep up though, I promise! -_-

It's completely up to the posters on how they want to do it though, to each their own, right?

zody

Member for 2 years

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The Health-Care PAC to Watch? Dentists (WSJ)

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My Molesters

The next event came when I was 15, a freshman in high school. I was at the house of a friend, ?Diane.? We had been doing homework together, and it was time for me to go. It was winter, cold and dark, so her father offered to give me a ride. He was a quiet man, a bit of a nebbish, and on the brief ride we talked innocuously about school. He pulled up just short of the driveway to my home, turned off the engine, then turned to face me. His voice choked with emotion, he started babbling about how men have sexual needs. If a man?s wife won?t have sex, he said, that leaves him angry and frustrated. I knew I should just open the door, but I was so shocked that I froze. Then he lunged at me, a hand on each breast, his face pressed to mine. I pushed him away, got out of the car, and ran into my house.

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Supply Chain Manager Advisor ? All jobs (page 2)

Supply Chain Manager Advisor

Information:

Posted: 20 Jun 2012
Apply deadline: 18 Sep 2012
Location: Switzerland

Job description:

Supply Chain Manager Advisor Switzerland
18227
THE ROLE
An international oil and gas company has requested CCL to recruit an experienced Supply Chain Manager Advisor to be based in Europe. Willing to travel as required. Rate and T&Cs negotiable.
THE PERSON
10+ years Consultancy experience in the oil & gas sector. Worked with or alongside the major consultancy firms in Supply Chain Management / Oil & Gas. Experience of de-centralised Supply Chain Management and Engineering business environments, global service and supply environment and distribution channels. Support, assist, guide and advise Project Managers on delivery of projects. Achieve project objectives, namely clearly defined, unified and lean Supply Chain Management processes across the company. Enable Supply Chain Management to support growth strategy, and to become a valued business partner to our internal customers.
QUALIFICATIONS REQUIRED
Qualified to Post Graduate or equivalent level. Extensive hands-on consultancy experience in Supply Chain Management and Contracts & Procurement. Complete understanding of Business Transformation and Change Management models. Understands business environment of a small / medium sized O&G operator. Good understanding of business environments in West Africa / emerging nations. Well versed in best practice in upstream O&G. Researches / implements fit for purpose solutions. Assertive, lateral thinker will search for solutions outside the box. Organised self-starter. First language English, with working knowledge of French language advantageous.

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Jobs: 101 ? 150 of 14895

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20 Jun 2012		Principal Metallurgical Engineer	Toronto, ON, Canada
20 Jun 2012		Senior Mine Engineer	Snow Lake, Manitoba, Canada
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20 Jun 2012		Senior Exploration Manager	Africa
20 Jun 2012		Development Chemist	Papua New Guinea
20 Jun 2012		Process Engineer	USA
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20 Jun 2012		Senior Exploration Geologist	Colorado, USA
20 Jun 2012		Mining & Geological Engineering Manager	South Dakota, USA
20 Jun 2012		Industrial Electrician	Tucson, Arizona, USA
20 Jun 2012		Senior Reservoir Engineer	Sydney, NSW, Australia (for residents)
20 Jun 2012		Technical Design Team Leader	Australia (for residents)
20 Jun 2012		Senior Electrical Engineer	QLD, Australia (for residents)
20 Jun 2012		Senior Mechanical Engineer	Australia (for residents)
20 Jun 2012		Rotating Equipment Engineer	Houston, Texas, USA
20 Jun 2012		Offshore Structural Engineer	Houston, Texas, USA
20 Jun 2012		Mechanical Static Engineer	Houston, Texas, USA
20 Jun 2012		Planner/Scheduler	Houston, Texas, USA
20 Jun 2012		Sr?Control Systems Designer	Houston, Texas, USA
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20 Jun 2012		Contract Offshore Onboard PFC Production Operations Rep	Halifax City, Nova Scotia, Canada
20 Jun 2012		Wireline Operators	Mount Pearl, Newfoundland & Labrador, Canada
20 Jun 2012		Supply Chain Manager Advisor	Switzerland
20 Jun 2012		Lead Instrumentation Engineer	Nigeria
20 Jun 2012		Geologist?? Exploration	Calgary, AB, Canada
20 Jun 2012		Accounts Payable Analyst?? Oil & Gas?? Direct Hire	Houston, Texas, USA
20 Jun 2012		HSE Manager?? Oil & Gas, Prefer Exp. with Rigs and Drilling + Field Operations	International
20 Jun 2012		Oilfield Safety Professional	Williston, North Dakota, USA
20 Jun 2012		Concrete Finisher	Bakersfield, California, USA
20 Jun 2012		Project Manager	Calgary, Alberta, Canada
20 Jun 2012		Oilfield Electronics Technician	Williston, North Dakota, USA
20 Jun 2012		Welding & Coating Supervisor	Iran
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20 Jun 2012	Hot!	Senior Piping Stress Analysis Expert	Iran
19 Jun 2012	Free!	Chief Exploration Geoscientist	Mauritania
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19 Jun 2012	Free! Hot!	Analista de?RH?Sr.	Brazil
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Structure of RNAi complex now crystal clear

Public release date: 20-Jun-2012
[ | E-mail | Share ]

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

CAMBRIDGE, Mass. (June 20, 2012) Researchers at the Whitehead Institute and Memorial Sloan-Kettering Cancer Center have defined and analyzed the crystal structure of a yeast Argonaute protein bound to RNA. This complex plays a key role in the RNA interference (RNAi) pathway that silences gene expression. Describing the molecular structure of a eukaryotic Argonaute protein has been a goal of the RNAi field for close to a decade.

"You can learn a lot from biochemical experiments, but to more fully understand a protein like Argonaute, it's useful to know where all of the atoms are and which amino acids are playing important roles," says Whitehead Institute Member David Bartel, who is also an MIT professor of biology and a Howard Hughes Medical Institute (HHMI) investigator. "Learning the Argonaute crystal structure is an important step in understanding the RNAi biochemical pathway and will be the basis for many future experiments."

The yeast Argonaute structure is described in the June 21st print issue of Nature.

In humans and most other eukaryotes, the RNAi pathway can reduce cellular protein production by reducing the proteins' RNA templates. By exploiting this pathway, scientists are able to knock down the expression of specific proteins and thereby determine their roles within the cell or organism. The RNAi pathway has also been of considerable interest for the treatment of human disease.

RNAi depends on two proteins, Dicer and Argonaute. Dicer recognizes double-stranded RNA (dsRNA), latches onto it, and chops it into pieces 21-23 nucleotides long. Argonaute recognizes the dsRNA bits, discards one strand, and uses the other as a guide. When a single-stranded RNA matches the guide RNA's sequence, Argonaute cleaves the targeted RNA, thereby preventing it from serving as a template for protein production.

To determine the structure of Argonaute, Bartel and graduate student David Weinberg partnered with Kotaro Nakanishi in Dinshaw Patel's lab at Sloan-Kettering. Although the team expected to solve the structure of Argonaute alone, they were surprised to find that the protein came along with small bits of RNA that were also observed in the structure. The incorporation of these RNAs had switched the protein into an activated state that contained a four-component active site, the identification of which solved a longstanding mystery of what constituted the "missing" fourth component. With the structure of this complex in hand, scientists now have a better understanding for how it works.

"Seeing the crystal structure of a eukaryotic Argonaute for the first time was very excitingit's such a large protein with a complicated topology and many moving parts," says Weinberg. "It's a really impressive molecular machine."

###

This work was supported by National Institutes of Health (NIH), the Human Frontier Science Program, the Japan Society for the Promotion of Science, and the National Science Foundation (NSF).

Written by Nicole Giese Rura

David Bartel is a Member at Whitehead Institute for Biomedical Research, where his laboratory is located and all his research is conducted. He is also a Howard Hughes Medical Institute Investigator and a professor of biology at Massachusetts Institute of Technology.

Full Citation:

"Structure of yeast Argonaute with guide RNA"

Nature. June 21, 2012.

Kotaro Nakanishi (1,4), David E. Weinberg (2,3,4), David P. Bartel (2,3) & Dinshaw J. Patel (1).

1. Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
2. Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
3. Howard Hughes Medical Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
4. These authors contributed equally to this work.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 20-Jun-2012
[ | E-mail | Share ]

Contact: Nicole Giese Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

CAMBRIDGE, Mass. (June 20, 2012) Researchers at the Whitehead Institute and Memorial Sloan-Kettering Cancer Center have defined and analyzed the crystal structure of a yeast Argonaute protein bound to RNA. This complex plays a key role in the RNA interference (RNAi) pathway that silences gene expression. Describing the molecular structure of a eukaryotic Argonaute protein has been a goal of the RNAi field for close to a decade.

"You can learn a lot from biochemical experiments, but to more fully understand a protein like Argonaute, it's useful to know where all of the atoms are and which amino acids are playing important roles," says Whitehead Institute Member David Bartel, who is also an MIT professor of biology and a Howard Hughes Medical Institute (HHMI) investigator. "Learning the Argonaute crystal structure is an important step in understanding the RNAi biochemical pathway and will be the basis for many future experiments."

The yeast Argonaute structure is described in the June 21st print issue of Nature.

In humans and most other eukaryotes, the RNAi pathway can reduce cellular protein production by reducing the proteins' RNA templates. By exploiting this pathway, scientists are able to knock down the expression of specific proteins and thereby determine their roles within the cell or organism. The RNAi pathway has also been of considerable interest for the treatment of human disease.

RNAi depends on two proteins, Dicer and Argonaute. Dicer recognizes double-stranded RNA (dsRNA), latches onto it, and chops it into pieces 21-23 nucleotides long. Argonaute recognizes the dsRNA bits, discards one strand, and uses the other as a guide. When a single-stranded RNA matches the guide RNA's sequence, Argonaute cleaves the targeted RNA, thereby preventing it from serving as a template for protein production.

To determine the structure of Argonaute, Bartel and graduate student David Weinberg partnered with Kotaro Nakanishi in Dinshaw Patel's lab at Sloan-Kettering. Although the team expected to solve the structure of Argonaute alone, they were surprised to find that the protein came along with small bits of RNA that were also observed in the structure. The incorporation of these RNAs had switched the protein into an activated state that contained a four-component active site, the identification of which solved a longstanding mystery of what constituted the "missing" fourth component. With the structure of this complex in hand, scientists now have a better understanding for how it works.

"Seeing the crystal structure of a eukaryotic Argonaute for the first time was very excitingit's such a large protein with a complicated topology and many moving parts," says Weinberg. "It's a really impressive molecular machine."

###

This work was supported by National Institutes of Health (NIH), the Human Frontier Science Program, the Japan Society for the Promotion of Science, and the National Science Foundation (NSF).

Written by Nicole Giese Rura

David Bartel is a Member at Whitehead Institute for Biomedical Research, where his laboratory is located and all his research is conducted. He is also a Howard Hughes Medical Institute Investigator and a professor of biology at Massachusetts Institute of Technology.

Full Citation:

"Structure of yeast Argonaute with guide RNA"

Nature. June 21, 2012.

Kotaro Nakanishi (1,4), David E. Weinberg (2,3,4), David P. Bartel (2,3) & Dinshaw J. Patel (1).

1. Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
2. Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
3. Howard Hughes Medical Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
4. These authors contributed equally to this work.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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